Publications

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Predictive and therapeutic implications of a novel PLCy1/SHP2-driven mechanism of cetuximab resistance in metastatic colorectal cancer

By:

André Mansinho, MD, MSc

Journal: Clinical Cancer Research

Published Date: March 15, 2022

Evorpacept alone and in combination with pembrolizumab or trastuzumab in patients with advanced solid tumors (ASPEN-01): a first-in-human, open-label, multicentre, phase 1 dose-escalation and dose-expansion study

By:

Nehal Lakhani, MD, PhD

Journal: Lancet Oncol

Published Date: November 15, 2021

Safety, antitumor activity, and pharmacokinetics of dostarlimab, an anti-PD-1, in patients with advanced solid tumors: a dose-escalation phase 1 trial

By:

Amita Patnaik, MD, FRCPC, Drew W. Rasco, MD

Journal: Cancer Chemother Pharmacol.

Published Date: November 8, 2021

T cell engagers in solid tumors kick the door down

By:

Emiliano Calvo, MD, PhD, Maria de Miguel, MD

Journal: Cancer Cell

Published Date: November 8, 2021

First-in-Human Study of PF-06647020 (Cofetuzumab Pelidotin), an Antibody-Drug Conjugate Targeting Protein Tyrosine Kinase 7, in Advanced Solid Tumors

By:

Emiliano Calvo, MD, PhD, Manish R. Sharma, MD, Nehal Lakhani, MD, PhD, Victor Moreno, MD, PhD

Journal: Clin Cancer Res.

Published Date: August 15, 2021

Association of Concomitant Bone Resorption Inhibitors With Overall Survival Among Patients With Metastatic Castration-Resistant Prostate Cancer and Bone Metastases Receiving Abiraterone Acetate With Prednisone as First-Line Therapy

By:

Irene Moreno, MD

Journal: JAMA

Published Date: July 1, 2021

Combination Immunotherapy With IDO Inhibitors: Defining a Future Through Biomarker-Guided Patient Selection

By:

William B. McKean, MD

Journal: ASCO Daily News

Published Date: June 24, 2021

Blocking TIM-3 in Treatment-refractory Advanced Solid Tumors: A Phase Ia/b Study of LY3321367 with or without an Anti-PD-L1 Antibody

By:

Amita Patnaik, MD, FRCPC, Emiliano Calvo, MD, PhD, Maria de Miguel, MD

Journal: AACR Clinical Cancer Research

Published Date: April 15, 2021

T-cell–engaging Therapy for Solid Tumors

By:

Emiliano Calvo, MD, PhD, Maria de Miguel, MD, Victor Moreno, MD, PhD

Journal: AACR Clinical Cancer Research

Published Date: March 15, 2021

HERVs establish a distinct molecular subtype in stage II/III colorectal cancer with poor outcome

By:

André Mansinho, MD, MSc

Journal: NPJ genomic medicine

Published Date: February 15, 2021