Publications

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Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRASG12C Mutation

By:

Maria de Miguel, MD

Journal: New England Journal of Medicine (NEJM)

Published Date: August 23, 2023

Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer

By:

André Mansinho, MD, MSc

Journal: Cell Reports Medicine

Published Date: August 15, 2023

CDK9 INHIBITORS: a promising combination partner in the treatment of hematological malignancies

By:

Daniel Morillo, MD, Gala Vega, MD, Victor Moreno, MD, PhD

Journal: Oncotarget

Published Date: August 7, 2023

SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy

By:

Manish R. Sharma, MD

Journal: Cancer Discov.

Published Date: August 4, 2023

A first-in-human study of the fibroblast activation protein-targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors

By:

Emiliano Calvo, MD, PhD, Irene Moreno, MD, Tatiana Hernández, MD, Victor Moreno, MD, PhD

Journal: Sci Transl Med

Published Date: May 10, 2023

Activity of eftozanermin alfa plus venetoclax in preclinical models and patients with acute myeloid leukemia

By:

Daniel Morillo, MD, Emiliano Calvo, MD, PhD

Journal: Blood

Published Date: April 27, 2023

Patient-specific comorbidities as prognostic variables for survival in myelofibrosis

By:

Andrew L. Sochacki, MD

Journal: Blood Advances

Published Date: March 2, 2023

A Phase 1, First-in-Human, Dose-Escalation Study of MGD024, a CD123 x CD3 Bispecific Dart® Molecule, in Patients with Relapsed or Refractory CD123-Positive (+) Hematologic Malignancies

By:

Andrew L. Sochacki, MD, Manish R. Sharma, MD

Journal: Blood

Published Date: November 15, 2022

First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors

By:

Maria de Miguel, MD

Journal: AACR Clinical Cancer Research

Published Date: August 15, 2022

First-in-Human Dose-Escalation Study of Cyclin-Dependent Kinase 9 Inhibitor VIP152 in Patients with Advanced Malignancies Shows Early Signs of Clinical Efficacy

By:

Daniel Morillo, MD, Victor Moreno, MD, PhD

Journal: Clin Cancer Res.

Published Date: April 1, 2022