Predictive and therapeutic implications of a novel PLCy1/SHP2-driven mechanism of cetuximab resistance in metastatic colorectal cancer Leave a Comment / Publication / Joel E Predictive and therapeutic implications of a novel PLCy1/SHP2-driven mechanism of cetuximab resistance in metastatic colorectal cancer Read More »
Evorpacept alone and in combination with pembrolizumab or trastuzumab in patients with advanced solid tumors (ASPEN-01): a first-in-human, open-label, multicentre, phase 1 dose-escalation and dose-expansion study Leave a Comment / Publication / Joel E Evorpacept alone and in combination with pembrolizumab or trastuzumab in patients with advanced solid tumors (ASPEN-01): a first-in-human, open-label, multicentre, phase 1 dose-escalation and dose-expansion study Read More »
Safety, antitumor activity, and pharmacokinetics of dostarlimab, an anti-PD-1, in patients with advanced solid tumors: a dose-escalation phase 1 trial Leave a Comment / Publication / Joel E Safety, antitumor activity, and pharmacokinetics of dostarlimab, an anti-PD-1, in patients with advanced solid tumors: a dose-escalation phase 1 trial Read More »
T cell engagers in solid tumors kick the door down Leave a Comment / Publication / Joel E T cell engagers in solid tumors kick the door down Read More »
First-in-Human Study of PF-06647020 (Cofetuzumab Pelidotin), an Antibody-Drug Conjugate Targeting Protein Tyrosine Kinase 7, in Advanced Solid Tumors Leave a Comment / Publication / Joel E First-in-Human Study of PF-06647020 (Cofetuzumab Pelidotin), an Antibody-Drug Conjugate Targeting Protein Tyrosine Kinase 7, in Advanced Solid Tumors Read More »
Association of Concomitant Bone Resorption Inhibitors With Overall Survival Among Patients With Metastatic Castration-Resistant Prostate Cancer and Bone Metastases Receiving Abiraterone Acetate With Prednisone as First-Line Therapy Leave a Comment / Publication / Joel E Association of Concomitant Bone Resorption Inhibitors With Overall Survival Among Patients With Metastatic Castration-Resistant Prostate Cancer and Bone Metastases Receiving Abiraterone Acetate With Prednisone as First-Line Therapy Read More »
Combination Immunotherapy With IDO Inhibitors: Defining a Future Through Biomarker-Guided Patient Selection Leave a Comment / Publication / Joel E Combination Immunotherapy With IDO Inhibitors: Defining a Future Through Biomarker-Guided Patient Selection Read More »
Blocking TIM-3 in Treatment-refractory Advanced Solid Tumors: A Phase Ia/b Study of LY3321367 with or without an Anti-PD-L1 Antibody Leave a Comment / Publication / Joel E Blocking TIM-3 in Treatment-refractory Advanced Solid Tumors: A Phase Ia/b Study of LY3321367 with or without an Anti-PD-L1 Antibody Read More »
T-cell–engaging Therapy for Solid Tumors Leave a Comment / Publication / Joel E T-cell–engaging Therapy for Solid Tumors Read More »
HERVs establish a distinct molecular subtype in stage II/III colorectal cancer with poor outcome Leave a Comment / Publication / Joel E HERVs establish a distinct molecular subtype in stage II/III colorectal cancer with poor outcome Read More »