Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRASG12C Mutation Leave a Comment / Publication / Joel E Single-Agent Divarasib (GDC-6036) in Solid Tumors with a KRASG12C Mutation Read More »
Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer Leave a Comment / Publication / Joel E Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer Read More »
CDK9 INHIBITORS: a promising combination partner in the treatment of hematological malignancies Leave a Comment / Publication / Joel E CDK9 INHIBITORS: a promising combination partner in the treatment of hematological malignancies Read More »
SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy Leave a Comment / Publication / Joel E SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid Tumors to Re-treatment with Targeted Therapy Read More »
A first-in-human study of the fibroblast activation protein-targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors Leave a Comment / Publication / Joel E A first-in-human study of the fibroblast activation protein-targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors Read More »
Activity of eftozanermin alfa plus venetoclax in preclinical models and patients with acute myeloid leukemia Leave a Comment / Publication / Joel E Activity of eftozanermin alfa plus venetoclax in preclinical models and patients with acute myeloid leukemia Read More »
Patient-specific comorbidities as prognostic variables for survival in myelofibrosis Leave a Comment / Publication / Joel E Patient-specific comorbidities as prognostic variables for survival in myelofibrosis Read More »
A Phase 1, First-in-Human, Dose-Escalation Study of MGD024, a CD123 x CD3 Bispecific Dart® Molecule, in Patients with Relapsed or Refractory CD123-Positive (+) Hematologic Malignancies Leave a Comment / Publication / Joel E A Phase 1, First-in-Human, Dose-Escalation Study of MGD024, a CD123 x CD3 Bispecific Dart® Molecule, in Patients with Relapsed or Refractory CD123-Positive (+) Hematologic Malignancies Read More »
First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors Leave a Comment / Publication / Joel E First-In-Human Phase I Study of the OX40 Agonist MOXR0916 in Patients with Advanced Solid Tumors Read More »
First-in-Human Dose-Escalation Study of Cyclin-Dependent Kinase 9 Inhibitor VIP152 in Patients with Advanced Malignancies Shows Early Signs of Clinical Efficacy Leave a Comment / Publication / Joel E First-in-Human Dose-Escalation Study of Cyclin-Dependent Kinase 9 Inhibitor VIP152 in Patients with Advanced Malignancies Shows Early Signs of Clinical Efficacy Read More »